A compound consisting of an adenosine molecule bonded to one acidic phosphate group, present in most DNA and RNA. It often exists in a cyclic form with the phosphate bonded to the nucleoside at two points.
- Phosphate is necessary for the generation of adenosine triphosphate from adenosine diphosphate and adenosine monophosphate and other crucial phosphorylation reactions.
- These effectors can assume a vast diversity of chemical forms, ranging from simple inorganic molecules to complex nucleotides such as cyclic adenosine monophosphate (cAMP).
- Drugs that inhibit phosphodiesterase, the enzyme that catalyzes the breakdown of adenosine triphosphate to cyclic adenosine monophosphate, enhance cardiac contractility in heart failure.
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