Definition of amitriptyline in English:

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Pronunciation: /ˌamiˈtriptəˌlēn/ Pronunciation: /-lin/


An antidepressant drug of the tricyclic group, with a mild tranquilizing action.
Example sentences
  • Tricyclic antidepressants, including amitriptyline, can cause weight gain, drowsiness, and anticholinergic symptoms.
  • The most useful drugs are anticonvulsants, especially gabapentin and carbamazepine, and tricyclic antidepressants, especially amitriptyline.
  • Of the tricyclic antidepressants, amitriptyline appears to be the most efficacious in the treatment of diabetic neuropathy when compared to placebo.


1960s: from ami(ne) + tri- + (he)ptyl + -ine4.

For editors and proofreaders

Syllabification: am·i·trip·ty·line

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