Definition of amyotrophic lateral sclerosis in English:

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amyotrophic lateral sclerosis

Pronunciation: /ˌāˌmīəˌträfik ˌladərəl skləˈrōsəs/


A progressive degeneration of the motor neurons of the central nervous system, leading to wasting of the muscles and paralysis. Also called ALS, Lou Gehrig's disease.
Example sentences
  • Patients with alcoholism, drug abuse, cancer, multiple sclerosis, psychosis, amyotrophic lateral sclerosis, parkinsonism, Down syndrome, liver or kidney disease, epilepsy and stroke were excluded from the study.
  • The differential diagnosis includes any condition that can result in myelopathy, such as multiple sclerosis, amyotrophic lateral sclerosis and masses (such as metastatic tumors) that press on the spinal cord.
  • Other conditions, such as multiple sclerosis, amyotrophic lateral sclerosis and tumors on the spinal cord, can cause similar symptoms.


Late 19th century: amyotrophic from amyotrophy.

For editors and proofreaders

Syllabification: a·my·o·troph·ic lat·er·al scle·ro·sis

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