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antagonism Syllabification: an·tag·o·nism
Pronunciation: /anˈtaɡəˌnizəm/

Definition of antagonism in English:


1Active hostility or opposition: the antagonism between them his antagonism toward the local people petty antagonisms and jealousies
More example sentences
  • And there often is an assumption that it is about hostility or antagonism between men and women.
  • The symbolic separation and opposition aside, the personal antagonism between the two men is not imagined by the media.
  • The petty point-scoring highlights the deepening antagonism between the rivals.
1.1 Biochemistry Inhibition of or interference with the action of one substance or organism by another.
Example sentences
  • This concept helps link mutualism to antagonisms such as herbivory, predation, and parasitism, interactions defined largely by the existence of costs.
  • In order to understand the structural basis for pterin antagonism, selected derivatives were docked into the NOS pterin binding cavity.
  • As in biochemistry, antagonism in pharmacology is not restricted to competition.


Early 19th century: from French antagonisme, from Greek antagōnizesthai 'struggle against' (see antagonist).

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