Definition of antagonize in English:

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antagonize

Pronunciation: /anˈtaɡəˌnīz/

verb

[with object]
1Cause (someone) to become hostile: he antagonized many colleagues during the budget wars
More example sentences
  • Why go out of the way to offend and antagonize religious people?
  • It is spending astronomical amounts of money, alienating allies and further antagonizing opponents.
  • I fully admit I have gone out of my way on more than one occasion to needle and to antagonize him.
Synonyms
arouse hostility in, alienate;
rub the wrong way
1.1 Biochemistry (Of a substance) act as an antagonist of (a substance or its action): two other drugs antagonized the antidepressantlike effect
More example sentences
  • For example, oxytocin's calming effects are enhanced by estrogen, but antagonized by androgen, she notes.
  • Another approach is using drugs to antagonise the peripheral effects of opioids so that bowel dysfunction is reversed, speeding discharge from hospital.
  • They also found that ADHD children responded variably to different B vitamins, with pyridoxine and thiamine antagonizing each other's benefits.

Origin

Mid 18th century (in the sense 'struggle against'): from Greek antagōnizesthai, from ant- 'against' + agōnizesthai 'struggle' (from agōn 'contest').

For editors and proofreaders

Syllabification: an·tag·o·nize

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