Having no electrical polarity.
- As is well known, the surface tension between water and an apolar medium of low dielectric constant increases with increasing salt concentration.
- These binding surfaces are generally larger and more apolar than those of three-state binding complexes such as that involving antibody-antigen complexes.
- In general, the pore-lining residues are hydrophobic, which would create an apolar seal and prevent the passage of ions.
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