Bleeding from the uterus occurring between menstrual periods, a side effect of some oral contraceptives.
- The most common side effects are nausea and vomiting, breakthrough bleeding and spotting, headaches, bloating or swelling, and breast tenderness.
- Concomitant use of rifampin and oral contraceptive pills can lead to breakthrough bleeding and an increased risk of pregnancy.
- Side effects of breast tenderness and breakthrough bleeding, concerns about breast and ovarian cancer, gall bladder disease, and thromboembolic events, may all contribute to low adherence rates.
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Syllabification: break·through bleed·ing
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