The initiation of cancer formation.
- Chemoprevention of cancer aims to prevent, arrest, or reverse either the initiation phase of carcinogenesis or the progression of neoplastic cells to cancer.
- Thus, the association of reactive oxygen species both in carcinogenesis and in cancer progression has been shown in numerous investigations.
- An altered apoptotic response represents a pivotal feature of cancer, contributing to carcinogenesis and resistance to therapy.
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