A serious fungal disease of the lungs and other tissues, endemic in the warmer, arid regions of America.
- The most common cause of benign calcified pulmonary lesions is the granulomatous reaction to infectious or foreign agents, such as tuberculosis, coccidioidomycosis, and silicosis.
- Although a histoplasmin test is a good screening test, it often cross-reacts in patients with coccidioidomycosis.
- If initial antibody testing is negative, but clinical suspicion of coccidioidomycosis is high, repeat testing is indicated because it may take a month or more to develop measurable antibody titers.
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