Partial or total obstruction of a coronary artery, usually resulting in a myocardial infarction (heart attack).
- Then came the breakthrough discoveries that thrombotic coronary occlusion caused myocardial infarction and that balloon catheters could cross the occlusion, squash the thrombus, and re-establish flow.
- The mechanisms responsible for acute ischemia include fissure and/or rupture of plaque, stimulation and aggregation of platelets, and eventual thrombus formation, with resultant coronary occlusion.
- He had a second coronary occlusion and repeated by-pass surgery in 1990, and he shared insight into the mental disability he experienced following this procedure and described the time required for recovery.
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