Definition of cyclic GMP in English:
A cyclic version of the nucleotide guanosine monophosphate. In cellular metabolism, it is a secondary messenger affecting cell growth and division.
- The carbon monoxide activates the enzyme guanylyl cyclase, as does nitric oxide, regulating the intracellular levels of the second messenger cyclic GMP, which in turn regulates cellular activity.
- A second messenger of internal cellular communication - cyclic GMP, produced in response to nitric oxide - is a key regulator of vascular smooth muscle cell contractility, growth, and differentiation.
- The resulting vasodilation has been potentially attributed to inhibition of cyclic nucleotide phosphodiesterases, with resulting increases in intracellular levels of cyclic AMP and cyclic GMP accompanied by decreases in Ca.
What do you find interesting about this word or phrase?
Comments that don't adhere to our Community Guidelines may be moderated or removed.
Most popular in the US
Most popular in the UK
Most popular in Canada
Most popular in Australia
Most popular in Malaysia
Most popular in Pakistan