Definition of de novo in English:

de novo

Syllabification: de no·vo
Pronunciation: /dā ˈnōvō, di
 
/

adverb & adjective

Starting from the beginning; anew: [as adverb]: in a pure meritocracy, everyone must begin de novo [as adjective]: a general strategy for de novo protein design
More example sentences
  • Both the Federal Reserve and the Office of the Comptroller of the Currency recommend that Congress remove outdated barriers to de novo interstate branching.

Origin

early 17th century: Latin, literally 'from new'.

Definition of de novo in:

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Word of the day brannigan
Pronunciation: ˈbranɪg(ə)n
noun
a brawl or violent argument