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deafferentation Syllabification: de·af·fer·en·ta·tion
Pronunciation: /dēˌafərenˈtāSHən/

Definition of deafferentation in English:


The interruption or destruction of the afferent connections of nerve cells, performed especially in animal experiments to demonstrate the spontaneity of locomotor movement.
Example sentences
  • On the other hand, in REM sleep, the respiratory variability persists even after deafferentation, suggesting that central REM processes underlie the variability.
  • It is believed that lateral ankle ligament injury results in not only mechanical instability but also ligamentous deafferentation, contributing to instability.
  • Despite extensive chest wall deafferentation, the intensity and quality of dyspnea are not altered in patients with spinal cord injury in whom work of breathing is increased by bronchoconstriclion.


Pronunciation: /dēˈafəˌrentid/
Example sentences
  • Lurie has received an award of $20,000 as an administrative supplement to conduct research regarding PTP1C increases in the deafferented auditory brainstem.
  • A deafferented pupil constricts consensually, but not to direct light, paradoxically enlarging when the light is quickly brought from the unaffected side (Marcus Gunn pupil).
  • Next he restrained the monkeys' healthy forelimbs, compelling them to reuse the deafferented limbs, which they otherwise avoided doing.
Definition of deafferentation in:
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