The removal of an amino group from an amino acid or other compound.
- The earliest enzymatic functions are mostly linked to amino acid catabolism: deamination, transamination, and decarboxylation.
- The liver, influenced by protein intake and anabolic need, makes urea from deamination of amino acids in the Krebs urea cycle.
- DNA bases are susceptible to hydrolytic deamination, although deamination is much less frequent in double-stranded compared to single-stranded DNA.
- Example sentences
- Among the deaminated bases, uracil, hypoxanthine and Xan are repaired by the base excision repair pathway in prokaryotic and eukaryotic cells.
- As a result, the deaminated product, urocanate, is not the usual a-keto acid associated with loss of a-amino nitrogens.
- Other members of the Solanaceae synthesize branched-chain fatty acids and in each of these cases, the primer for the extension of the alkane is proposed to be a deaminated branched-chain amino acid.
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