(abbreviation DDC or ddC)
A drug that inhibits the replication of HIV and is used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analog of a pyrimidine nucleoside.
- We depleted NT2 cells of their endogenous mtDNA by prolonged treatment with dideoxycytidine, thus creating the desired line.
- ‘Coined’ abbreviations such as HCTZ, AZT, T3, PCN, U, and ddC are not acceptable medical abbreviations, may be misinterpreted, and may cause drug errors.
- The CNS distribution of ddC is similar to that of ddI in humans.
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