Definition of disulfiram in English:


Syllabification: di·sul·fir·am
Pronunciation: /dīˈsəlfəˌram


  • A synthetic compound used in the treatment of alcoholics to make drinking alcohol produce unpleasant aftereffects. Also called Antabuse ( • trademark ).
    • Alternative name: tetraethylthiuram disulfide; chemical formula: (C2H5)2NCSSCN(C2H5)2
    More example sentences
    • The rationale for disulfiram in treating alcoholism is that most alcoholics taking disulfiram will not drink for fear of getting sick.
    • Occasionally the modestly toxic disulfiram (Antabuse ®) is useful.
    • Consuming alcohol after taking disulfiram results in symptoms such as palpitations, flushing, nausea, vomiting, and headache.


1940s: blend of disulfide (see disulfide) and thiuram (from thio- + urea + amide).

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