Definition of endonuclease in English:

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Pronunciation: /ˌendōˈn(y)o͞oklēˌās/ Pronunciation: /-ˌāz/


An enzyme that cleaves a polynucleotide chain by separating nucleotides other than the two end ones.
Example sentences
  • Total DNA was prepared from leaves of barley after 7 days of germination and restricted with appropriate endonucleases.
  • Let us remember that they are concerned with a DNA endonuclease, so I had some experience dealing with an enzyme that cut nucleic acids.
  • Primers and endonucleases are used in the cloning of the various constructs.

For editors and proofreaders

Syllabification: en·do·nu·cle·ase

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