Definition of hypertonic in English:

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Pronunciation: /ˌhīpərˈtänik/


1Having increased pressure or tone, in particular.
Example sentences
  • Increasing concentrations of hypertonic saline were administered, each for 5 minutes.
  • She was treated with topical corticosteroids, ofloxacin, and a 5% sodium chloride hypertonic solution.
  • The use of hypertonic mannitol to treat severe cerebral edema is at the physician's discretion.
1.1 Biology Having a higher osmotic pressure than a particular fluid, typically a body fluid or intracellular fluid.
Example sentences
  • Vasopressin continued to act in patients excreting isotonic or hypertonic urine, so hypotonic intake must be avoided in them.
  • In hypertonic syndromes the brain compensates by increasing osmoles in the brain cells.
  • Neurologically they are hypertonic and may have frequent episodes of apnea.
1.2 Physiology Of or in a state of abnormally high muscle tone.
Example sentences
  • Whilst the muscles are not necessarily hypertonic in osteoporosis they are likely to have undergone fibrotic changes.
  • When the nervous system becomes involved, the muscle tendon bundles remain hypertonic and pain reflexes in the area are activated.



Pronunciation: /-ˈtōnēə/
Example sentences
  • The springs in this territory are also of a great help in curing cardiovascular diseases like hypertonia.
  • Massive overdose can bring about ginseng abuse syndrome, which is characterized by hypertension, insomnia, hypertonia, and edema.
  • If the patient survives the initial episode, the disorder leads to severe mental and motor retardation, growth failure, hypertonia and seizures.


Pronunciation: /ˌhīpərtəˈnisitē/
Example sentences
  • The hypertonicity of the radiopaque agent draws fluid into the bowel to facilitate passage and expulsion of the tenacious meconium.
  • Infant colic is characterized by excessive and inconsolable crying, hypertonicity, and wakefulness, mainly in the evening.
  • This vicious cycle forces the fissure open and prevents healing, which in turn exacerbates the sphincter hypertonicity.
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