nounchiefly Anatomy & Biology
1The action or process of being turned inside out or folded back on itself to form a cavity or pouch.
- This indicates a level of plasma membrane invagination comparable with mammalian skeletal muscle.
- In the chick embryo, for example, the ectoderm initially expresses L-CAM; during neural plate invagination, however, L-CAM expression is replaced by that of N-cadherin.
- Catheters with multiple side holes on several planes are less likely to cause invagination of airway mucosa into the catheter than those with single side or end holes.
1.1A cavity or pouch so formed.
- Intranuclear cytoplasmic invaginations, similar to that seen in non-neoplastic hepatocytes (or in metastatic melanoma) are also frequent.
- These invaginations represent placental outgrowths and they extend towards the centre, enclosing the central hole into a triangular slit.
- As is typical, many of the latter showed reactive changes, such as large, variably sized nuclei; intranuclear invaginations; and multinucleation.
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