Definition of irritation in English:


Syllabification: ir·ri·ta·tion
Pronunciation: /ˌiriˈtāSHən


  • 1The state of feeling annoyed, impatient, or angry.
    More example sentences
    • And all without the slightest signs of irritation or impatience.
    • The impatience and irritation that was such a marked characteristic of New York is gone, replaced by a rare generosity and calm.
    • Instead, his look of irritation and slight anger remained, making her quickly look back down to the paper.
  • 1.1A cause of this: the minor irritations of life
    More example sentences
    • Naturally, this disability is attended by irritations, inconveniences, and some significant professional frustrations.
    • The stress, irritations, fears and hopes are excised through simple repetitive movement.
    • The entries cited in the catalogue deal with problems and irritations common to all portrait painters.
    irritant, annoyance, thorn in someone's side/flesh, bother, trial, torment, plague, inconvenience, nuisance, aggravation, pain (in the neck), headache, burr under someone's saddle
  • 1.2The production of inflammation or other discomfort in a bodily part or organ.
    More example sentences
    • Metaplastic changes are common lesions and occur in reaction to foreign substances or chronic irritation.
    • Endoscopy allows doctors to check for irritation, ulcers, inflammation and abnormal tissue growth in the internal organs.
    • Mosquito bites cause severe skin irritation through an allergic reaction to the insects' saliva.
  • 1.3 Biology The stimulation of an organism, cell, or organ to produce an active response.
    More example sentences
    • It has been shown that the mouse model has a predictive value for human responses to sensory irritation.
    • Initially, cellular growth increases markedly in an effort to regenerate tissue in response to irritation.


late Middle English: from Latin irritatio(n-), from the verb irritare (see irritate).

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