1The state of feeling annoyed, impatient, or angry.
- And all without the slightest signs of irritation or impatience.
- The impatience and irritation that was such a marked characteristic of New York is gone, replaced by a rare generosity and calm.
- Instead, his look of irritation and slight anger remained, making her quickly look back down to the paper.
1.1A cause of this: the minor irritations of life
More example sentences
- Naturally, this disability is attended by irritations, inconveniences, and some significant professional frustrations.
- The stress, irritations, fears and hopes are excised through simple repetitive movement.
- The entries cited in the catalogue deal with problems and irritations common to all portrait painters.
1.2The production of inflammation or other discomfort in a bodily part or organ.
- Metaplastic changes are common lesions and occur in reaction to foreign substances or chronic irritation.
- Endoscopy allows doctors to check for irritation, ulcers, inflammation and abnormal tissue growth in the internal organs.
- Mosquito bites cause severe skin irritation through an allergic reaction to the insects' saliva.
1.3 Biology The stimulation of an organism, cell, or organ to produce an active response.
- It has been shown that the mouse model has a predictive value for human responses to sensory irritation.
- Initially, cellular growth increases markedly in an effort to regenerate tissue in response to irritation.
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