Definition of knockout mouse in English:

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knockout mouse

noun

Genetics
A mouse whose DNA has been genetically engineered so that it does not express particular proteins.
Example sentences
  • Postdoctoral fellow Deborah Burks, lead author of the Nature paper, decided to examine fertility in the knockout mice.
  • Liver regeneration is impaired in iNOS gene knockout mice.
  • More importantly, researchers can use knockout mice to develop better models of many inherited human diseases.
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