Definition of light chain in English:

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light chain


A protein subunit that, as one of a pair, forms part of the main antigen-binding region of an immunoglobulin molecule.
Example sentences
  • Free kappa and lambda light chains are antibody fragments secreted by plasma cells in the bone marrow.
  • The complete dissociation of all of the regulatory light chains was a precondition of later experiments.
  • This assay is highly sensitive to increasing concentrations of monoclonal free kappa or free lambda light chains in the serum of patients with evolving or relapsing myelomas.

For editors and proofreaders

Syllabification: light chain

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