Definition of loperamide in English:

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Pronunciation: /lōˈperəˌmīd/


A synthetic drug of the opiate class that inhibits peristalsis and is used to treat diarrhea.
Example sentences
  • Effective antidiarrhoeal drugs such as loperamide and diphenoxylate can be used when necessary.
  • Empiric treatment of traveler's diarrhea with antibiotics and loperamide is effective and often limits symptoms to one day.
  • But treatment with an antibiotic and loperamide often can cure you within 24 hours.


1970s: probably from (ch)lo(ro-) + (pi)per(idine) + amide.

For editors and proofreaders

Syllabification: lo·per·a·mide

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