A genetic system that allows large proteins in immune system cells to identify compatible or foreign proteins. It allows the matching of potential organ or bone marrow donors with recipients.
- The classic example of genetic variation in the immune system is the major histocompatibility complex on chromosome 6.
- This would be consistent with evolution of variation in the major histocompatibility complex of the human immune system by infectious agents.
- The host's major histocompatibility complex is the part of the immune system that presents antigens to various immune system cells.
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