The process by which mechanical stimuli are translated into neuronal impulses. It is the physiological basis for sense experiences such as touch, hearing, and balance.
- The interpretation of this observation was that the periplasmic loop had been proteolysed, that its integrity was not essential for mechanosensation, but that its cleavage enhanced mechanosensitivity.
- Blount and co-workers have recently detected a four amino acid motif NxxD in the TM1 helix and have speculated that it could represent a sensor in mechanosensation.
- In prokaryotes, mechanosensation is apparently limited to the detection of osmotic forces manifested as intracellular turgor pressure.
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