Definition of methylate in English:

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Pronunciation: /ˈmeTHəˌlāt/


[with object] (often as adjective methylated)
1Mix or impregnate with methanol or methylated spirit.
1.1 Chemistry Introduce a methyl group into (a molecule or compound).
Example sentences
  • Some molecules are heavily methylated while others are not, consistent with our previous observations.
  • The ability of these compounds to methylate DNA, however, correlated with the biological activity.
  • When this hydroxyl group is then methylated to give there is a very significant, 3000-fold, decrease in inhibitor binding.



Pronunciation: /ˌmeTHəˈlāSHən/
Example sentences
  • DNA methylation is a common molecular alteration in colorectal cancer cells.
  • Thus it not only had nucleosomes and histone acetylation and methylation, but was also sexual with meiosis and a bouquet stage.
  • After methylation, DNA was extracted with phenol-chloroform followed by ethanol precipitation.

For editors and proofreaders

Syllabification: meth·yl·ate

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