Definition of mithridatize in English:

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mithridatize

Pronunciation: /ˌmiTHrəˈdādīz/

verb

[with object] rare
Render immune against a poison by administering gradually increasing doses of the poison.
Example sentences
  • Few possibilities to stay awake at 4am, since I am completely mithridatized with caffeine since my student years: An espresso at 2am is 100% helpless, no effect at all.
  • And to crown it all, it mithridatized the Ethiopian people to the future secession of Eritrea by incorporating the right of unconditional secession in the Transition Charter.
  • The film is really very lovely, and I am NOT saying that because I am by now sufficiently mithridatized to no longer cringe when I see myself on a screen.

Origin

Mid 19th century: from the name of Mithridates (see Mithridates VI), who reputedly made himself immune to poisons by constantly taking antidotes, + -ize.

For editors and proofreaders

Syllabification: mith·ri·da·tize

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