Definition of mono- in English:

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Pronunciation: /ˈmänō/
(also mon- before a vowel)


1One; alone; single: monorail
1.1With an extreme, singular character to the point of dominance or exclusion: monolithic monomania monopoly
2 Chemistry (Forming names of compounds) containing one atom or group of a specified kind: monoamine


From Greek monos 'alone'.

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