Definition of mutation in English:

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Pronunciation: /myo͞oˈtāSH(ə)n/


1The action or process of mutating: the mutation of ethnic politics into nationalist politics his first novel went through several mutations
More example sentences
  • As a matter of fact, the functions of books have undergone a process of mutation, and the underlying motivating force is now nothing but the soaring prices.
  • Variation accumulates over time through a random process of mutation.
  • It commits the artist to a descent into time, into the processes of mutation, decay and dissolution.
2The changing of the structure of a gene, resulting in a variant form that may be transmitted to subsequent generations, caused by the alteration of single base units in DNA, or the deletion, insertion, or rearrangement of larger sections of genes or chromosomes.
Example sentences
  • The same pattern appears in tumor-associated genes undergoing either loss-of-function mutation or rearrangements.
  • Mere mutation of the gene structure cannot fully explain the ‘spiritual’ evolution of species.
  • The gene mutation appears to work by restricting calorie absorption at the cellular level.
2.1A distinct form resulting from a change in the structure of a gene.
Example sentences
  • Kidney tumors and estrogen-treated kidneys have mutations in microsatellites.
  • It is important to realize that mutations in different mutant individuals are not necessarily distinct.
  • The first is that this was a naturally occurring mutation in the Siamese.
mutant, freak (of nature), deviant, monstrosity, monster, anomaly
3 Linguistics Regular change of a sound when it occurs adjacent to another, in particular.
3.1(In Germanic languages) the process by which the quality of a vowel was altered in certain phonetic contexts; umlaut.
3.2(In Celtic languages) change of an initial consonant in a word caused (historically) by the preceding word. See also lenition.



Pronunciation: /-SHənl/
Example sentences
  • Consider a chromosome that is divided into two regions, one of which contains multiple mutational hot spots.
  • This runaway process, described as the mutational meltdown, eventually leads to extinction.
  • Besides single step mutational events, some multiple steps mutational events were also observed.


Pronunciation: /-SHənl-ē/
Example sentences
  • The data were used to estimate the number of mutationally defined genes collectively deleted by the deficiencies.
  • A data set with numerous X and autosomal genes could give repeatability of Ks, but this may represent repeatability at the chromosomal level (and be mutationally driven) rather than be on account of selection on silent sites.
  • By testing several cutoff values for each tree, it is possible to determine what fraction of positions is mutationally saturated, and those positions are omitted from further phylogenetic analysis.


Pronunciation: /ˈmyo͞otətiv/
Example sentences
  • Already, the replicative and mutative technologies of cloning and morphing have obliged us to review the complacent assumption of our unique ontological status as human subjects.
  • He closed his hood over his face, cutting off all eyesight, and dove into the mutative wall of sand, letting its punishing currents bounce him inward like a bird riding on gale-swells.
  • But we never see the mutative capabilities of the individuals themselves.


Late Middle English: from Latin mutatio(n-), from mutare 'to change'.

Words that rhyme with mutation

ablation, aeration, agnation, Alsatian, Amerasian, Asian, aviation, cetacean, citation, conation, creation, Croatian, counterdemonstration, counterproliferation, crustacean, curation, Dalmatian, delation, dilation, donation, duration, elation, fixation, Galatian, geolocation, glocalization, gyration, Haitian, halation, Horatian, ideation, illation, lavation, legation, libation, location, lunation, natation, nation, negation, notation, nutation, oblation, oration, ovation, potation, relation, rogation, rotation, Sarmatian, sedation, Serbo-Croatian, station, staycation, taxation, Thracian, vacation, vexation, vocation, zonation

For editors and proofreaders

Syllabification: mu·ta·tion

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