Definition of nucleosome in English:

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nucleosome

Pronunciation: /ˈn(y)o͞oklēəˌsōm/

noun

Biology
A structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a core of histones.
Example sentences
  • Histone proteins are essential components of nucleosomes in eukaryotic chromosomes.
  • The packaging of DNA with histones into nucleosomes and higher-order chromatin structures has profound effects on transcription initiation.
  • DNA replication, like other DNA-dependent processes, must contend with the organization of DNA into nucleosomes and higher-order chromatin structures.

Derivatives

nucleosomal

Pronunciation: /ˌn(y)o͞oklēəˈsōməl/
adjective
Example sentences
  • The failure to recover mutations in genes encoding nucleosomal histones in this screen may be due to the presence of numerous copies of the histone gene cluster in flies.
  • Histones are small basic proteins encoded by a multigene family and are responsible for the nucleosomal organization of chromatin in eukaryotes.
  • In wild-type cells, the repressed state spreads unidirectionally through nucleosomal chromatin.

For editors and proofreaders

Syllabification: nu·cle·o·some

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