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osteogenesis imperfecta Syllabification: os·te·o·gen·e·sis im·per·fec·ta
Pronunciation: /ästēōˌjenəsəs impərˈfektə/

Definition of osteogenesis imperfecta in English:


An inherited disorder characterized by extreme fragility of the bones.
Example sentences
  • For example, children with an inherited condition known as osteogenesis imperfecta have bones that are brittle and more susceptible to breaking.
  • Three children with severe osteogenesis imperfecta received allogeneic bone marrow transplants; in two osteoblast engraftment was shown.
  • Kwanini, who suffers from osteogenesis imperfecta (brittle bone disease), has been in a wheelchair since the age of nine.


Modern Latin, from osteogenesis + Latin imperfecta 'imperfect' (feminine of imperfectus).

Definition of osteogenesis imperfecta in:

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