Definition of ototoxic in English:

ototoxic

Syllabification: o·to·tox·ic
Pronunciation: /ˌōtəˈtäksik
 
/

adjective

Medicine
  • Having a toxic effect on the ear or its nerve supply.
    More example sentences
    • Exposure to solvents alone significantly increased the risk for hearing loss, most likely the result of ototoxic effects along the auditory pathway.
    • Simultaneous administration of several ototoxic agents or prolonged treatment with high dosages of an ototoxic medication should be avoided when possible.
    • These medications must be administered carefully in patients who are elderly, have poor renal function, require a prolonged course of medication, or require simultaneous administration of multiple ototoxic agents.

Derivatives

ototoxicity

Pronunciation: /-täkˈsisitē/
noun
More example sentences
  • The safety profile of the formulation is generally favorable, with no demonstrable ototoxicity, nephrotoxicity, bone marrow suppression, or cardiovascular adverse effects.
  • However, it is thought that patients with little to no drainage at the time of surgery who may be at highest risk for ototoxicity because of the lack of inflammation of the middle car mucosa to decrease the round window permeability.
  • The potential medicolegal implications of ototoxicity, therefore, have created a dilemma: we need to determine which topical antibiotic is safe and effective in treating patients with chronic discharge from their ears.

More definitions of ototoxic

Definition of ototoxic in:

Get more from Oxford Dictionaries

Subscribe to remove adverts and access premium resources

Word of the day skosh
Pronunciation: skəʊʃ
noun
a small amount; a little