Definition of paracrine in English:

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paracrine

Pronunciation: /ˈperəkrən/

adjective

Physiology
Relating to or denoting a hormone that has effect only in the vicinity of the gland secreting it.
Example sentences
  • It was suggested that beta-cell cAMP levels in islets are greater than those in dispersed cells due to the paracrine secretion of glucagon by islet a-cells, which was expected to increase release rate and lead to faster bursting.
  • To assess the possible involvement of a paracrine mechanism, normal human keratinocytes were exposed to SSR and culture medium was collected 24 h later.
  • Here, we systematically derive discrete models of cell-to-cell communication from a mechanistic description of autocrine and paracrine signaling in epithelial layers.

Origin

1970s: from para-1 'beside' + a shortened form of endocrine or exocrine.

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