Definition of pharmacophore in English:
A part of a molecular structure that is responsible for a particular biological or pharmacological interaction that it undergoes.
- This pharmacophore identifies two important hydrogen-bonding interactions at opposite ends of the ligand.
- The phenothiazine ring is a well-known pharmacophore, and chlorpromazine is a prototype of this class of antipsychotic drugs.
- The similar mechanism of action of paclitaxel, the epothilones, discodermolide and eleutherobin has led to the suggestion that these structurally dissimilar substances possess common pharmacophores.
Definition of pharmacophore in:
- British & World English dictionary
What do you find interesting about this word or phrase?
Comments that don't adhere to our Community Guidelines may be moderated or removed.
Most popular in the US
Most popular in the UK
Most popular in Canada
Most popular in Australia
Most popular in Spain
Most popular in Malaysia
Most popular in India
Most popular in Pakistan