Definition of phosphodiesterase in English:

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phosphodiesterase

Pronunciation: /ˌfäsfōdīˈestərās/

noun

Biochemistry
An enzyme that breaks a phosphodiester bond in an oligonucleotide.
Example sentences
  • Calf spleen phosphodiesterase, snake venom phosphodiesterase and alkaline phosphatase were from Roche Molecular Biochemicals (Meylan, France).
  • Its mechanism of action is thought to involve inhibition of cyclic adenosine monophosphate phosphodiesterase and enhancement of the effect of prostaglandin I2.
  • In isolated cilia and in intact olfactory receptor neurons, studies have shown basal activities of both adenylate cyclase and cAMP phosphodiesterase.

For editors and proofreaders

Syllabification: phos·pho·di·es·ter·ase

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