Definition of polypeptide in English:

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Pronunciation: /ˌpälēˈpeptīd/


A linear organic polymer consisting of a large number of amino-acid residues bonded together in a chain, forming part of (or the whole of) a protein molecule.
Example sentences
  • It is a basic protein with a single polypeptide chain and acts on cellular and model lipid membranes.
  • These enzymes break down proteins into polypeptides and then into amino acids, which are absorbed through the gut wall into the bloodstream.
  • They both develop random transient beta-strands across the whole polypeptide chain.


Early 20th century: from poly- 'many' + peptone + -ide.

For editors and proofreaders

Syllabification: pol·y·pep·tide

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