Definition of proline in English:

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Pronunciation: /ˈprōˌlēn/


An amino acid that is a constituent of most proteins, especially collagen.
  • A heterocyclic compound; chemical formula: C5H9NO2.
Example sentences
  • Active oxygen species cause protein damage through direct interaction with specific amino acids (lysine, arginine, proline or threonine).
  • The amount of the amino acids threonine, proline and histidine were also increased in roots of slag-cultivated maize plants.
  • The cationic component of the hemolymph is frequently replaced by potassium and free amino acids such as glutamate, proline, lysine and glycine.


Early 20th century: contraction of the chemical name p(yr)rol(id)ine-2-carboxylic acid.

For editors and proofreaders

Syllabification: pro·line

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