A protein complex in cells containing proteases; it breaks down proteins that have been tagged by ubiquitin.
- In the context of the cell, the unfolding process participates in several important steps in cellular physiology, such as protein turnover in proteasomes.
- Among the archaebacterial-specific genes several ribosomal proteins, DNA metabolic enzymes, and proteasome subunits are prominent.
- The proteasome and other endoproteolytic enzymes are located in the cytosol and may also be involved in the catabolism of larger fragments.
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