Definition of prozone in English:

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Pronunciation: /ˈprōzōn/


(In testing for antigens) the range of relative quantities of precipitin (or agglutinin) and antigen within which any precipitation (or agglutination) is inhibited by the predominance of one component.
Example sentences
  • In addition, these tests may show a ‘prozone’ phenomenon in which large amounts of antibody block the antibody-antigen reaction, causing a false-negative test in the undiluted sample.
  • However, highly concentrated antibodies may result in a prozone effect, leading to decreased intensity of staining.


Early 20th century: from pro-2 'before' + (agglutination) zone.

For editors and proofreaders

Syllabification: pro·zone

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