An oxidized derivative of pyridoxine that acts as a coenzyme in transamination and other processes.
- This conversion is catalyzed by the ATP requiring enzyme, pyridoxal kinase.
- B6 vitamers are first oxidized to pyridoxal, and rapidly phosphorylated to P5P in the liver.
- The central domain is typical of class 1 pyridoxal - 5'-phosphate-dependent enzymes.
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