Definition of replicase in English:

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Pronunciation: /ˈrepliˌkās/ Pronunciation: /-ˌkāz/


An enzyme that catalyzes the synthesis of a complementary RNA molecule using an RNA template.
Example sentences
  • Q-beta replicase based gene amplification: This approach involves production of RNA in the amplification reaction using QB replicase as the enzyme and reaction at fixed temperature.
  • The estimate is based on a large mutational target, the 804-base TMV MP gene that encodes the viral movement protein, which is a cognate sequence for the viral replicase.
  • As a replicase, Pol is highly sensitive to template defects and misinserts nucleotides only extremely rarely.


1960s: from the verb replicate + -ase.

For editors and proofreaders

Syllabification: rep·li·case

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