Definition of Santa Cruz in English:

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Santa Cruz

1ˌsantə ˈkro͞ozˌsäntä ˈkro͞os A city in central Bolivia; population 1,561,061 (2009).
2ˌsantə ˈkro͞ozˌsäntä ˈkro͞oT͟H A port and the chief city of the island of Tenerife, in the Canary Islands; population 192,000. Full name Santa Cruz de Tenerife.
3A city in west central California, on Monterey Bay; population 56,124 (est. 2008).

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Syllabification: San·ta Cruz

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