Definition of scleroderma in English:


Syllabification: scle·ro·der·ma
Pronunciation: /ˌskli(ə)rəˈdərmə, ˌskler-


  • A chronic hardening and contraction of the skin and connective tissue, either locally or throughout the body.
    More example sentences
    • Diseases as disparate as scleroderma, cystic fibrosis, kyphoscoliosis, sleep apnea, and sickle cell disease were found to have shared consequences in the pulmonary circulation.
    • People with this disorder have signs and symptoms of three diseases - lupus, scleroderma and polymyositis.
    • Rheumatic diseases such as rheumatoid arthritis, lupus, dermatomyositis, and scleroderma are thought to be autoimmune diseases.

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Word of the day coloratura
Pronunciation: ˌkɒlərəˈtjʊərə
elaborate ornamentation of a vocal melody