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sclerosis Syllabification: scle·ro·sis
Pronunciation: /skləˈrōsəs/

Definition of sclerosis in English:


1Abnormal hardening of body tissue.
Example sentences
  • In MS, myelin is lost in multiple areas, leaving scar tissue called sclerosis.
  • The lymph node biopsy showed sclerosis surrounding cellular nodules that contained clusters of large atypical cells admixed with small lymphocytes and numerous eosinophils.
  • It exhibited squamous differentiation, sclerosis, and eosinophilia.
2Excessive resistance to change: the challenge was to avoid institutional sclerosis
More example sentences
  • In other words, this is a story not about institutional sclerosis, but about the necessarily contingent process of institutional change.


Late Middle English (originally denoting a hard external tumor): via medieval Latin from Greek sklērōsis, from sklēroun 'harden'.

Words that rhyme with sclerosis

apotheosis, chlorosis, cirrhosis, diagnosis, halitosis, hypnosis, kenosis, meiosis, metempsychosis, misdiagnosis, mononucleosis, myxomatosis, necrosis, neurosis, osmosis, osteoporosis, prognosis, psittacosis, psychosis, symbiosis, thrombosis, toxoplasmosis, trichinosis, tuberculosis
Definition of sclerosis in:
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