Marijuana of a variety that has a particularly high concentration of psychoactive agents.
- A bottle of whiskey, a spliff of sinsemilla, it didn't matter, as long as it took the edge off.
- If someone moved from relatively weaker resin to smoking home-grown sinsemilla, known as skunk, there would be the risk of acute anxiety triggered off by increased levels of THC.
1970s: from American Spanish, literally 'without seed'.
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