A hormone that acts as an intermediate in the stimulation of tissue growth by growth hormone.
- IGF-I (originally called somatomedin C) is a growth factor structurally related to insulin.
- This is accomplished through development of several small proteins called somatomedin which are formed in the liver.
- Because the liver also is a primary source of somatomedins, an estrogenic stimulus might ultimately increase somatomedin concentrations.
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