Definition of someone's number is up in English:
informal The time has come when someone is doomed to die or suffer some other disaster or setback.
[with reference to a lottery number or a number by which one may be identified]
- Although it must be tempting to tell someone that you love that you love them when you know your number is up, if you also know the true perpetrator of a crime that someone else is suspected of, surely you are duty bound to blurt that out first.
- It doesn't seem to displace much air hence they have little warning, and once they come in contact with the ‘strings’, their number is up!
- He has even arranged for his body to be returned to Tibet for a traditional sky burial when his number is up.
Definition of someone's number is up in:
- British & World English dictionary