noun (plural synostoses /-sēz/)Physiology & Medicine
The union or fusion of adjacent bones by the growth of bony substance, either as a normal process during growth or as the result of ankylosis.
- Isolated sagittal synostosis, premature fusion of the sagittal suture, is the most common type of craniosynostosis and accounts for 56% to 58% of reported cases.
- Familial nonsyndromic craniosynostosis, which affects 2 to 6 percent of infants with sagittal synostosis and 8 to 14 percent of infants with coronal synostosis, is transmitted as an autosomal dominant disorder.
- There may be partial or complete fusion of a suture, but a short segment of synostosis often produces the same deformity as a complete fusion.
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