Definition of tachyphylaxis in English:


Syllabification: tach·y·phy·lax·is
Pronunciation: /ˌtakəfiˈlaksis


  • Rapidly diminishing response to successive doses of a drug, rendering it less effective. The effect is common with drugs acting on the nervous system.
    More example sentences
    • Trebling doses of histamine diphosphate were chosen instead of the usual doubling dose because of the half-life of lidocaine, the number of challenges, and the need to minimize possible tachyphylaxis of the histamine effect.
    • The efficacy of calcipotriene is comparable to mid-potency topical corticosteroids; however, it does not cause skin atrophy or tachyphylaxis.
    • This spirometric improvement was maintained throughout the 13-week period without any evidence of tachyphylaxis.

More definitions of tachyphylaxis

Definition of tachyphylaxis in:

Get more from Oxford Dictionaries

Subscribe to remove adverts and access premium resources

Word of the day coloratura
Pronunciation: ˌkɒlərəˈtjʊərə
elaborate ornamentation of a vocal melody