Definition of topoisomer in English:

topoisomer

Syllabification: top·o·i·so·mer
Pronunciation: /ˌtäpōˈīsəmər
 
/

noun

Biochemistry
A topologically distinct isomer, especially of DNA.
More example sentences
  • The distribution of 2 plasmid DNA topoisomers was measured by Southern blot analysis with a radiolabeled 2 DNA probe.
  • Comparing the topoisomer distribution of plasmid DNA from the ancestor with the completely relaxed plasmid control yielded an estimate of = - 0.066 for the ancestor.
  • An extract was deemed to be deficient if, in all three trials, the ratio of intermediate to supercoiled products indicated an accumulation of intermediate topoisomers (compared to wild type).

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